If launching on VDI using VMware Horizon Client, disconnect and reconnect. This should remove any temp files and clear up space.
If you are launching on a personal device, you may need to clear up some drive space (if unable to free up space, try connecting to the VMware Horizon Client to launch Solidworks 2020/21).
Virtualization Error
Remove Solidworks 2020/21 from Cloudpaging player and re-launch from AppsAnywhere.